DMLOM-S Tablet


Diclofenac potassium BP 50 mg
Serratiopeptidase IP 10 mg

(Alu Alu) (10 x 10)

Diclofenac is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. Serratiopeptidase is a proteolytic enzyme (protease) produced by enterobacterium Serratia sp. E-15 used in the prevention of pain and swelling.

Indications and Usage

⇒ For the treatment of primary dysmenorrhea
⇒ For the treatment of mild to moderate pain
⇒ For the relief from the signs and symptoms of osteoarthritis
⇒ For the relief from the signs and symptoms of rheumatoid arthritis
⇒ Chronic inflammation
⇒ Headaches, muscle and joint pain
⇒ Serious diseases like cancer and heart disease
⇒ Superficial thrombophlebitis
⇒ Postoperative & traumatic swelling
⇒ Acute or chronic ear, nose or throat disorder

Rationale of Combination

Product Description:- Diclofenac potassium is used as an anti-inflammatory agent to pacify mild to moderate pain and inflammation. Common conditions associated with pain and inflammation include arthritis, trauma, surgery and fibermyalgia. Additionally, serratiopeptidase helps to reduce fluid retention in affected areas, which contributes to proper drainage and a quicker recovery.


Diclofenac Potassium:-

Diclofenac is an acetic acid non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac inhibits the production of prostaglandins by inhibiting COX-1 and COX-2 pathways thereby exhibiting anti- inflammatory effects.

Absorption: Well absorbed following oral administration.
Distribution: widely distributed in animals. Plasma protein binding exhibited is >99%.
Elimination: hepatic metabolism leads to elimination through urine.


Serratiopeptidase is an enzyme isolated from a non-pathogenic bacteria called enterobacteria Serratia E15. Serratiopeptidase has powerful anti-inflammatory properties and is particularly useful for post-traumatic swelling, fibrocystic breast disease and bronchitis. It is able to digest dead tissue, blood clots, cysts, and arterial plaques.

Absorption: On oral administration, serratiopeptidase is absorbed in GI tract.
Distribution: Distributed throughout the body tissues, unchanged via systemic circulation. It reaches in higher concentration in inflamed tissues. Serratiopeptidase levels in inflammatory exudates rises gradually with decline in blood levels indicating that serratiopeptidase is quite rapidly transferred to the site of inflammation.

Adverse Effects

⇒Skin rash
⇒ Diarrhea
⇒Gastrointestinal disturbance
⇒ Noseblee
⇒ Dizziness


Diclofenac sodium and Serratiopeptidase is contraindicated in patients with active GI bleeding or perforations, asthma, renal or hepatic disorders, hypertension, porphyria, peri-operative pain in CABG surgery patients and bleeding disorders.

Drug Interactions

Diclofenac potassium and Serratiopeptidase should not be taken concomitantly with other NSAIDs, anticoagulants including low-dose/LMW heparin, sucralfate, triamterene, cyclosporine, cholestyramine, colestipol, digoxin, aspirin, methotrexate and lithium.

Other Interactions:- Diclofenac potassium and Serratiopeptidase should be taken with food. Take the drug immediately after meals to avoid GI disturbances.


Store at 15-30°C.